Jayaraman Receives NSF CAREER Award
Posted in Faculty on Wednesday, June 3rd, 2009
COLLEGE STATION, Texas, June 3, 2009 – Arul Jayaraman, assistant professor in the Artie McFerrin Department of Chemical Engineering, has been awarded a Faculty Early Career Development (CAREER) Award sponsored by the National Science Foundation (NSF).
As a recipient of the prestigious award, Jayaraman will receive $400,000 throughout the next five years for his research, which is aimed at developing an integrated research and educational program in molecular systems biology (MSB). His project focuses on soluble signal-mediated signaling between bacteria and human cells, termed inter-kingdom (IK) signaling, as the research paradigm for MSB.
Jayaraman, who completed his undergraduate career at the Birla Institute of Technology and Science in India, earned his Ph.D. at the University of California, Irvine in 1998. He was an instructor in bioengineering at Harvard Medical School for four years prior to joining Texas A&M in 2004.
At Texas A&M, Jayaraman’s research focuses on investigating molecular mechanisms underlying inflammatory diseases and bacterial infections using integrated experimental and modeling approaches. His research projects include systems biology of interleukin-6 signaling in liver inflammation; metabolic engineering and proteomics of adipocytes during hypertrophic enlargement; and role of quorum sensing signaling in bacterial communication and infection.
His NSF-funded research has the potential to impact several areas, he says, noting the molecular systems signaling framework to be developed in the project will lead to a fundamental understanding of signals, receptors and recognition mechanisms. This, in turn, will further the advancement of emerging areas such as synthetic biology, Jayaraman says.
In addition, the research is expected to form the basis of novel molecular therapeutic strategies against E. coli and other pathogens, Jayaraman explains. The microfluidic tools and reporter cells to be developed in this work can be applied to other paradigms in biology and medicine where spatio-temporal behavior is important, he notes. Also, the dynamic profiling method utilized in this project will synergistically further efforts in computational systems biotechnology through the development of new models and algorithms for describing biomolecular dynamics and interactions, Jayaraman says.
The CAREER Award was established to support junior faculty within the context of their overall career development, combining in a single program the support of research and education of the highest quality and in the broadest sense. Through this program, the NSF emphasizes the importance on the early development of academic careers dedicated to stimulating the discovery process in which the excitement of research is enhanced by inspired teaching and enthusiastic learning.













